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IGARD

Primary Location
51 Cuppage Road #01-04
Singapore, Singapore 229469
Phone: 65 6732 3233

Office Hours

DayMorningAfternoon
Monday10.30 - 1212 - 6
Tuesday10.30 - 1212 - 6
Wednesday10.30 - 1212 - 6
Thursday10.30 - 1212 - 6
Friday10.30 - 1212 - 6
Saturday10.30 - 1212 - 6
SundayClosedClosed
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Atropine Eye-Drops for Myopia Control

Atropine was first introduced as a means of myopia control in the 1920s although large scale research studies are much more recent. It was believed that the eye-drops works by paralysing the accommodation of the eye, but more recent evidence suggest that myopia progression is slowed down via the effect of the anti-muscarinic biochemical on the sclera or retina.

A series of double-masked clinical trials has investigated atropine eye-drops in various concentrations for myopia control in Singaporean children. This is entitled "Atropine in the Treatment of Myopia (ATOM)" and results were published internationally on Ophthalmology in 2006 (ATOM1) and 2012 (ATOM2).

Results from ATOM1 showed that the instillation of atropine 1% eye-drop slowed down the progression of myopia by 77% compared to its placebo. However, atropine eye-drop users suffered from a significant rebound effect upon treatment cessation: Myopia progressed thereafter at a much higher rate, although the treated eyes were still considerably less myopic than the control group (average -4.29D vs. -5.22D) after three years.

Results from ATOM2 demonstrated the dose-response relationship of myopia control and its corresponding side-effects when atropine eye-drops are used in different levels of concentration.

Treatment Myopia Progression (Over 2 years)
1.0% Atropine -0.29D
0.5% Atropine -0.30D
0.1% Atropine -0.38D
0.01% Atropine -0.49D

Measures of visual function, such as accommodative amplitudes, visual acuities and pupil sizes, were considerably less affected in lower concentration. During the study, 70% of children on atropine 0.5% had requested for spectacles with a reading prescription in comparison to only 61% who were on atropine 0.1%. Only 6% of children on atropine 0.01% opted to do so.

Atropine eye-drops are widely used in Singapore in myopia control in children.

Find out more about <a href=" http://igard.com.sg/eye-exam/orthokeratology.html">Myopia Control with Orthokeratology Refractive Therapy.</a>

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Testimonial

IGARD is the best at what they do and make you feel right at home.

- Chris P. / Singapore, Singapore

Office Hours

**PUBLIC HOLIDAY - CLOSED**
DayMorningAfternoon
Monday10.30 - 1212 - 6
Tuesday10.30 - 1212 - 6
Wednesday10.30 - 1212 - 6
Thursday10.30 - 1212 - 6
Friday10.30 - 1212 - 6
Saturday10.30 - 1212 - 6
SundayClosedClosed

**PUBLIC HOLIDAY - CLOSED**
 

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65 6732 3233

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IGARD
51 Cuppage Road #01-04
Singapore, Singapore 229469
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